BIOSENSING AND BIOMARKER RESEARCH LABORATORY

We develop biosensors
to meet real-world needs.

We educate next-generation engineers.

Lab in the Media

Dr. Chang Liu featured on New England Weekend podcast

Dr. Chang Liu featured on New England Weekend podcast

Dr. Liu joined WBZ's New England Weekend to discuss the development of at-home HIV detection technologies and their potential to make HIV screening more accessible.

UMass researchers receive $1.3M for at-Home HIV test

UMass researchers receive $1.3M for at-Home HIV test

Dr. Liu received a new two-year, $1.3 million award from the National Institutes of Health to advance his proof-of-concept work toward commercialization.

UMass researchers discover new way to detect PFAS in water

Dr. Liu was interviewed by WAMC Northeast Public Radio about a new PFAS-detecting method developed in the lab. The findings were published in Science Advances.

New PFAS testing method created at UMass Amherst

Dr. Liu and Dr. Wei developed a new PFAS testing method, a promising step toward making water testing more affordable, portable and accessible

A PFAS testing method developed by Dr. Liu's lab is now on media!

ScienceDaily and EurekAlert reported a new PFAS testing method that Dr. Liu's lab had developed.

College of Engineering Welcomes Eight Talented New Faculty Members for the Fall of 2024

Dr. Liu and Dr. Wei joined the University of Massachusetts Amherst Department of Biomedical Engineering in Fall 2024.

Research

Point-Of-Care Testing and Lab Testing Assays and Devices for Protein Biomarkers of Various Diseases

Our lab has developed a click chemistry amplified nanopore (CAN) assay for ultrasensitive circulating antigen quantification.

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Point-Of-Care Testing and Lab Testing Assays and Devices for Protein Biomarkers of Various Diseases
click chemistry amplified nanopore (CAN) assayPublications

Machine Learning-Assisted Sequencing-by-Degradation for Single-Molecule Protein Sequencing

Our group designed a “Sequencing-by-Degradation (SBD)” method, in which the N-terminal AAs of a peptide sample is chemically derivatized and cleaved, and then identified by a nanopore in a cyclic manner to reconstitute its sequence.

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Machine Learning-Assisted Sequencing-by-Degradation for Single-Molecule Protein Sequencing
Sequencing-by-Degradation (SBD)Publications

Toxin and Pollutant Identification, Detection, and Interaction

We engineered nanopores by modifying the pore lumen with cyclodextrins as adapters to enable sensing of small PFAS molecules.

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Toxin and Pollutant Identification, Detection, and Interaction
PFASPublications
Meet the Lab

Meet the Lab

Latest Lab News

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Two PhD students in Biomedical Engineering joined the lab.

Three postdoctoral fellows and a PhD student in Biomedical Engineering joined the lab.